Inductive heating inside flow reactors

Published on December 9, 2011

The multistep flow synthesis of vinyl azides and their application in the synthesis of vinyltriazoles is explained. The required heat is generated by electromagnetic induction based on copper, which serves both as a heatable as well as catalytically active packed-bed material inside the flow reactor.

Kirschning Group | Leibniz Universität Hannover, Germany

Andreas Kirschning is a Professor at the Institute of Organic Chemistry, Leibniz Universität Hannover, Germany. His research interests include enabling technologies in organic synthesis and total synthesis and mutasynthesis of biologically active natural products. Lukas Kupracz and Jens Wegner are PhD students, Jan Hartwig is an M. Sc. student in the research group of Andreas Kirschning.

Sources

The original research article is published in the Open Access Beilstein Journal of Organic Chemistry and is part of the Thematic Series Chemistry in flow systems II.

Kupracz, L.; Hartwig, J.; Wegner, J.; Ceylan, S.; Kirschning, A., Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions, Beilstein J. Org. Chem. 2011, 7, 1441–1448. doi:10.3762/bjoc.7.168

The original research article is published in the Open Access Beilstein Journal of Organic Chemistry and is part of the Thematic Series Chemistry in flow systems II.

Kupracz, L.; Hartwig, J.; Wegner, J.; Ceylan, S.; Kirschning, A., Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions, Beilstein J. Org. Chem. 2011, 7, 1441–1448. doi:10.3762/bjoc.7.168

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